A statuesque blonde wakes up after five years in a coma. When she remembers who she is, the woman only called "The Bride" (Uma Thurman) also knows what she has to do: Take revenge on the people who spoiled her wedding day by slaughtering the congregation and the man who ordered it: Bill (David Carradine).

There was going to be blood. A lot of blood. And chopped-off limbs.

The first chapter places more emphasis on ridiculous martial arts action, anime and carnage.